SUMO Protease otherwise known as Ulp1, is a recombinant fragment of ULP1 (Ubl-specific protease 1) from Saccharomyces cerevisiae. This highly specific protease cleaves off sumo tags by recognizing the tertiary structure of SUMO as opposed to recognizing its amino acid sequence. Because of its recognition of SUMO’s tertiary structure, it has little to no non-specific proteolysis keeping your protein samples safe after all affinity tags have been cleaved off. SUMO protease is active from 2°C to 37°C in a P.H range of 7.0 – 9.0, for lower temperatures allow more time for the cleavage reaction.

SUMO Ulp1 Protease Information

SUMO Ulp1 Protease MSDS