Recombinant Human Kras(G12C), Gst-Tag

(For Research Use Only)

Availability: In stock

Catalog #	Amount	Price	Tiered Pricing	Qty
5727-4122G-50	50ug	$339.00
5727-4122G-100	100ug	$559.00

Please inquire about custom configurations or bulk packaging.

-OR- -OR-

Kras is a member of the RAS protein family, which are a class of small GTPases involved in cell signaling. As an oncogene mutated in several different cancers, the G12C substitution mutation favors the activated, GTP-bound state of the protein.

Recombinant Human Kras(G12C), Gst-Tag

Double click on above image to view full picture

More Views

Scientific Details

Bioactivity:

Bioactivity please see document file

Formulation:

PBS + 20% glycerol

Purification:

N-GST Tagged

Purity:

>95% by SDS-PAGE

Source:

E. Coli

Storage & Stability:

Stable for 12 months at -80°C, Avoid freeze/thaw cycles

Suggested Usage:

Used as a target for inhibition assays to develop treatment compounds for a variety of cancers.

Molecular Weight:

45.98 kDa

View / Download Product Data Sheets

Documentation:

Download PDF

Catalog #	Product Name
5727-4123BK	Kras (G12D) -cRAF Binding Assay Kit
5727-4127NK	Kras (G12R) Nucleotide Exchange Assay Kit
5727-4121BK	Kras (WT) -cRAF Binding Assay Kit
5727-4127G-GP	Recombinant Human Kras G12R, GST-Tag, GppNHp Loaded
5727-4128G-GP	Recombinant Human Kras G12V, GST-Tag, GppNHp Loaded
5727-4128NK-384	Kras (G12V) Nucleotide Exchange Assay Kit (384 reactions)
5727-4122G-GP	Recombinant Human Kras G12C, GST-Tag, GppNHp Loaded
5727-4128BK	Kras (G12V) -cRAF Binding Assay Kit
5727-4127BK	Kras (G12R) -cRAF Binding Assay Kit
5727-4122BK	Kras (G12C) -cRAF Binding Assay Kit
5727-4127G-G	Recombinant Human Kras G12R, GST-Tag, GDP Loaded
5727-4121NK-384	Kras (WT) Nucleotide Exchange Assay Kit (384 reactions)
5727-4123NK-384	Kras (G12D) Nucleotide Exchange Assay Kit (384 reactions)
5727-4123G-GP	Recombinant Human Kras G12D, GST-Tag, GppNHp Loaded
5727-4122NK-384	Kras (G12C) Nucleotide Exchange Assay Kit (384 reactions)
5727-4128G-G	Recombinant Human Kras (G12V), GST-Tag, GDP Loaded

References

1. Tam, I.Y., et al. Clin Cancer Res. 2006;12(5):1647-1653.

2. Fernández-Medarde A., et al. Genes (Basel). 2021;12(5):681.

Recombinant Human Kras(G12C), Gst-Tag

More Views

Scientific Details

View / Download Product Data Sheets

References

FOLLOW US