Recombinant Human DNA polymerase theta (POLQ) - C terminal Domain

(For Research Use Only)

Availability: In stock

Catalog #	Amount	Price
7657283-20 ug	20 ug	$399.00
7657283-100 ug	100 ug	$999.00
7657283-1 mg	1.0 mg	$2,999.00

Please inquire about custom configurations or bulk packaging.

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The Pol Theta C-terminal domain refers to a specific region found in the DNA polymerase theta enzyme (Pol θ). Pol θ is a specialized DNA polymerase that plays a role in DNA repair processes, particularly in the repair of double-stranded DNA breaks.

The C-terminal domain of Pol θ is located at the end of the enzyme's protein chain and is involved in various functions related to DNA repair. It contains specific motifs and regions that interact with other proteins and DNA molecules to facilitate repair processes.

Recombinant Human DNA polymerase theta (POLQ) - C terminal Domain

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Scientific Details

AA Sequence:

NM_199420.4 O75417, a. a. 1792-2590

Bioactivity:

For bioactivity please see document file

Formulation:

40 mM Tris pH 8.0, 150 mM KCl, 150 mM ammonium acetate, 10% glycerol, 1 mM TCEP, 1 mM PMSF, 1 mM Benzamidine

Purity:

>98% on SDS PAGE

Source:

E. coli

Storage & Stability:

Stable for 12 months at -80°C, Avoid freeze/thaw cycles

Suggested Usage:

DNA polymerase activity assay, Inhibitor screening for drug discovery, DNA repair mechanisms study

Molecular Weight:

90.97 kDa

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Documentation:

Download PDF

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7657643	Recombinant Human DNA polymerase theta (POLQ) N-terminal Helicase Domain
K777627	T7 High Yield RNA Synthesis Kit

Recombinant Human DNA polymerase theta (POLQ) - C terminal Domain

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Scientific Details

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