Plasmodium vivax lactate dehydrogenase (PvLDH) is an essential parasitic enzyme in the glycolytic pathway, widely used as a diagnostic biomarker and a measure of total-body parasite biomass in malaria infections. It catalyzes the interconversion of pyruvate and lactate for energy production. is a key target for rapid diagnostic tests (RDTs) and is structurally distinct from human LDH, making it a potential target for antimalarial drug development.