Recombinant Human SIRP-Alpha
SIRP-Alpha is a protein that is primarily expressed by natural killer cells, granulocytes, and some subsets of T cells. It plays a role in the regulation of immune responses, including the recognition and destruction of cancer cells, regulation of inflammation, and the resolution of infections. SIRP-Alpha binds to CD47, a protein that is upregulated on cancer cells, preventing them from being phagocytosed by macrophages. Inhibition of the SIRP-Alpha/CD47 interaction has been studied as a potential cancer therapy.
