Nsp7 is one cofactor of SARS-CoV-2 RNA polymerase complex and can significantly increase RdRp template binding and processivity. The viral polymerase is essential for the coronavirus replication. With the high evolutionary stability compared with surface proteins, SARS-CoV-2 RNA polymerase has become a major target of antiviral drugs.

SARS-CoV-2 NSP7 Information